ARC Polyclonal Antibody

Target Synonym: ARC;Arg3.1

Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Background: Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer in the nervous system. ARC protein is released from neurons in extracellular vesicles that mediate the transfer of ARC mRNA into new target cells, where ARC mRNA can undergo activity-dependent translation. ARC capsids are endocytosed and are able to transfer ARC mRNA into the cytoplasm of neurons. Acts as a key regulator of synaptic plasticity: required for protein synthesis-dependent forms of long-term potentiation (LTP and depression (LTD and for the formation of long-term memory.

Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.

Immunogen: Recombinant fusion protein of human ARC

Dilution: WB 1:500-1:2000

Calculated MW: 45kDa

Observed MW: 45kDa

• Artikelnummer: ELSE-AB-92941-120
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: E-AB-92941-120
• Verpackungseinheit: 120μL
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit
• Konjugat: Unconjugated