ATG7 Antibody: Biotin

Rabbit Anti-Human ATG7 Polyclonal

Target: ATG7.

Conjugate: Biotin.

Product Type: Polyclonal.

Immunogen: Synthetic peptide from the N-terminal of Human ATG7.

Swiss-Prot: O95352.

Purification: Peptide Affinity Purified.

Storage Buffer: PBS, 50% glycerol, 0.09% sodium azide.

Concentration: 1 mg/ml.

Specificity: Detects 77.9 kDa.

Cellular Localization: Cytoplasm, Preautophagosomal Structure .

Tissue Specificity: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.

Scientific Background: ATG7 in conjuction with ATG10, mediates the formation of the autophagosome when ATG12 is covalently bound to ATG5 and targets to autophagosome vesicles. It also activates ATG8, and is crucial for amino acid supply in neonates.

References: 1. Mizushima N., et al. (1998) J Biol Chem. 273: 33889-92.2. Mizushima N., et al. (1998) Nature. 395: 395-8.3. Suzuki K., et al. (2001) EMBO J. 20: 5971-81.4. Tanida I., et al. (1999) Mol Biol Cell. 10: 1367-79.5. Shintani T., et al. (1999) EMBO J. 18: 5234-41.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSPC-610D-BI
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SPC-610D-BI
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Human Gene ID: 10533
• Wirt: Rabbit