ATP6V0A4 Polyclonal Antibody, Rabbit

Abbreviation: ATP6V0A4

Target Synonym: ATP6V0A4;A4;ATP6N1B;ATP6N2;RDRTA2;RTA1C;RTADR;STV1;VPH1;VPP2

Conjugation: Unconjugated

UNIProt ID: Q9HBG4

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human ATP6V0A4

Dilution: WB 1:500-1:2000

• Artikelnummer: ELSE-AB-92785-200
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-92785-200
• Green Labware: Nein
• Verpackungseinheit: 200 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit