AXIN1 blocking peptide

AXIN1 blocking peptide
Artikelnummer
GTX89836-PEP-100
Verpackungseinheit
100 μg
Hersteller
GeneTex

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Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89836.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Concentration:

Background: This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]

Region Sequence: C-FEEKIIGKVEKVD

Full Name: axin 1
Mehr Informationen
Artikelnummer GTX89836-PEP-100
Hersteller GeneTex
Hersteller Artikelnummer GTX89836-PEP-100
Green Labware Nein
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
Methode ELISA, Blocking, Affinity Purification
Human Gene ID 8312
Produktinformation (PDF) Download
MSDS (PDF) Download