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Azide-PEG8-Val-Cit-PAB-MMAE
Azide-PEG8-Val-Cit-PAB-MMAE
Artikelnummer
BPS82277-1
Verpackungseinheit
1 mg
Hersteller
BPS Bioscience
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Products from BPS Bioscience require a minimum order value above 400€
Description: Azide-PEG8-Val-Cit-PAB-MMAE is a cleavable ADC linker which contains an azide, a PEG spacer, a Val-Cit dipeptide, a PAB group, and an MMAE warhead. The azide is free to participate in click chemistry with terminal alkynes or strained cyclooctynes such as DBCO or BCN. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient MMAE payload delivery via an elimination mechanism within the PAB structure.
Format: Solid
Purity: 0,98
Storage Stability: At least 6 months at -20°C.
Warnings: Avoid freeze/thaw cycles. See SDS for additional warnings and handling.
Biosafety Level: Not applicable (BSL-1)
Description: Azide-PEG8-Val-Cit-PAB-MMAE is a cleavable ADC linker which contains an azide, a PEG spacer, a Val-Cit dipeptide, a PAB group, and an MMAE warhead. The azide is free to participate in click chemistry with terminal alkynes or strained cyclooctynes such as DBCO or BCN. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient MMAE payload delivery via an elimination mechanism within the PAB structure.
Format: Solid
Purity: 0,98
Storage Stability: At least 6 months at -20°C.
Warnings: Avoid freeze/thaw cycles. See SDS for additional warnings and handling.
Biosafety Level: Not applicable (BSL-1)
| Artikelnummer | BPS82277-1 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 82277-1 |
| Verpackungseinheit | 1 mg |
| Mengeneinheit | STK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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