β-D-tetraacetylgalactopyranoside-PEG1-N3, CAS 153252-36-9

Product Description: β-D-tetraacetylgalactopyranoside-PEG1-N3 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. β-D-tetraacetylgalactopyranoside-PEG1-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C18H27N3O11

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 153252-36-9

Molecular Weight: 461.42

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• Artikelnummer: MEXHY-136318-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-136318-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK