B-Raf Polyclonal Antibody, Rabbit

Abbreviation: B-Raf

Target Synonym: BRAF; B-RAF1; B-raf; BRAF1; NS7; RAFB1; serine/threonine-protein kinase B-raf

Conjugation: Unconjugated

UNIProt ID: P15056

Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human B-Raf

Dilution: WB 1:500-1:2000

• Artikelnummer: ELSE-AB-92401-120
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-92401-120
• Green Labware: Nein
• Verpackungseinheit: 120 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit