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Encompassing Amino Acids: 35-242
Applications: Useful for studying protein binding interactions and screening inhibitors.
Description: Human secreted B7-1-Fc fusion protein, also known as CD80. GenBank Accession No. NM_005191, a.a. 35-242 expressed in a HEK293 cell expression system. MW = 50.5 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol, 1 mM DTT, 1 mM EDTA
Genbank: NM_005191
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Human IgG1)
Uniprot: P33681
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Byrum, J.N., Van Komen, J.S., Rodgers, W., J. Immunol. 2013 Sep 15;191(6):3073-3081.2. Legat, A., et al., Front Immunol. 2013 Dec 19;4:455.