B7-H2 (CD275, ICOSL), Fc fusion (Human) HiP™ Recombinant

Products from BPS Bioscience require a minimum order value above 400€

Encompassing Amino Acids: 19-258

Applications: Useful for the study of protein binding interactions, screening inhibitors, and selectivity profiling.

Description: Human secreted B7 homolog 2 (B7-H2)-Fc fusion protein, also known as CD275, ICOSL, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050, a.a 19-258 fused to human IgG1 Fc region (a.a. 100-330) and expressed in a HEK293 cell expression system. MW = 53.3 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 8.0.110 mM NaCl, 2.2 mM KCl and 20% glycerol

Genbank: NM_001283050

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal Fc fusion (Human IgG1)

Uniprot: O75144

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Guillonneau, C., et al., Transplantation. 2005; 80(4): 546-554.
2. Fan, X., et al., J. Exp. Med. 2014; 211(4): 715-725.

• Artikelnummer: BPS71130
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71130
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK