BCL10 antibody (BL10/2988R)

Clone Name: BL10/2988R

Application Note: ICC/IF: 1-2 μg/ml. IHC-P: 1-2 μg/ml. FACS: 1-2 μg/million cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 26

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Uniprot ID: O95999

Antigen Species: Human

Immunogen: Recombinant human BCL10 protein fragment (around aa122-168)

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: BCL10 immune signaling adaptor

• Artikelnummer: GTX02597-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02597-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Flow Cytometry, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 8915
• Wirt: Rabbit