Benoxaprofen, CAS 51234-28-7

Formulation: A solid

Formal Name: 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid

Purity: ≥98%

Formula Markup: C16H12ClNO3

Formula Weight: 301,7

Shelf life (days): 1460

CAS Number: 51234-28-7

Notes: Benoxaprofen is a non-steroidal anti-inflammatory drug.{64474} It inhibits prostaglandin E2 (PGE2; Item No. 14010) and leukotriene C4 (LTC4; Item No. 20210) production in isolated mouse peritoneal macrophages stimulated with A23187 (Item No. 11016 / 22030) when used at a concentration of 100 µM.{57231} Benoxaprofen (25 and 50 µg/ml) inhibits serum-induced chemotaxis of isolated rat peritoneal leukocytes.{64475} It induces hemolysis in isolated human erythrocytes and histamine release in isolated rat peritoneal mast cells in a light-dependent manner when used at a concentration of 10 µM.{64476} Benoxaprofen reduces carrageenan-induced paw edema and yeast-induced fever in rats and acetic acid-induced writhing in mice in a dose-dependent manner.{64474} Formulations containing benoxaprofen have previously been used in the treatment of osteoarthritis and rheumatoid arthritis.

• Artikelnummer: CAY36001-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36001-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe