Formulation: A solid
Formal Name: 3,5-bis(trifluoromethyl)benzyl (1R,5S,6s)-6-((1H-benzo[d][1,2,3]triazole-6-carboxamido)methyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
Purity: ≥98%
Formula Markup: C23H19F6N5O3
Formula Weight: 527,4
Shelf life (days): 1460
CAS Number: 2162961-71-7
Notes: BI-2545 is an inhibitor of autotaxin (IC50s = 2.2 and 3.4 for the human and rat enzyme, respectively).{40557} It is selective for autotaxin over a panel of 48 enzymes, transporters, ion channels, and receptors at 10 µM. BI-2545 (10 mg/kg) reduces plasma lysophosphatidic acid (LPA) levels in rats.