BimS BH3 (51-76) (human) (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-α-aspartyl-L-methionyl-L-arginyl-L-prolyl-L-α-glutamyl-L-isoleucyl-L-tryptophyl-L-isoleucyl-L-alanyl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucylglycyl-L-α-aspartyl-L-α-glutamyl-L-phenylalanyl-L-asparaginyl-L-alanyl-L-tyrosyl-L-tyrosyl-L-alanyl-L-arginyl-L-arginine, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C145H222N44O41S • XCF3COOH

Formula Weight: 3269,7

Shelf life (days): 1460

Notes: BimS BH3 (51-76) is a peptide that corresponds to amino acids 51-76 of the short splice variant of the pro-apoptotic protein Bim (BimS), which contains the Bcl-2 homology 3 (BH3) motif.{66171} It binds to myeloid cell leukemia-1 (Mcl-1), Bcl-xL, Bcl-2, and Bcl-W (IC50s = 18, 10, 7, and 18 nM, respectively). BimS BH3 (51-76) induces cytochrome c release from mitochondria derived from bcl-x-/- mouse embryonic fibroblasts (MEFs).

• Artikelnummer: CAY36963-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36963-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK
• Methode: Reinstoffe