Biotin Anti-Human CD127/IL-7RA Antibody(A019D5), Mouse, Monoclonal

Abbreviation: CD127/IL-7RA

Target Synonym: Interleukin-7 receptor subunit alpha;IL-7RA;CDw127;CD127;IL-7Rα;

Conjugation: Biotin

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Clone NO.: A019D5

UNIProt ID: P16871

Background: CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

Concentration: 0.5 mg/mL

• Artikelnummer: ELSE-AB-F1152B-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-F1152B-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Methode: Flow Cytometry
• Isotyp: Mouse IgG1 κ
• Human Gene ID: 3575
• Wirt: Mouse