Biotin Anti-Mouse CD51 Antibody(RMV-7), Rat, Monoclonal

Abbreviation: CD51

Target Synonym: Integrin alpha-V;αV integrin;Vitronectin Receptor;Integrin αV chain;ITGAV;

Conjugation: Biotin

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Clone NO.: RMV-7

UNIProt ID: P43406

Background: CD51 is a 140 kD protein, also known as αV?integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5?or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

Concentration: 0.5 mg/mL

• Artikelnummer: ELSE-AB-F1235B-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-F1235B-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Methode: Flow Cytometry
• Isotyp: Rat IgG1 κ
• Human Gene ID: 16410
• Wirt: Rat