BLNK blocking peptide

BLNK blocking peptide
Artikelnummer
GTX89949-PEP-100
Verpackungseinheit
100 μg
Hersteller
GeneTex

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Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89949.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Concentration:

Background: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]

Region Sequence: C-KDSTRLKYAVKVS

Full Name: B-cell linker
Mehr Informationen
Artikelnummer GTX89949-PEP-100
Hersteller GeneTex
Hersteller Artikelnummer GTX89949-PEP-100
Green Labware Nein
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus), Pig (Porcine), Dog (Canine), Cow (Bovine)
Methode ELISA, Blocking, Affinity Purification
Human Gene ID 29760
Produktinformation (PDF) Download
MSDS (PDF) Download