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Product Description: BMP-3 Protein, a TGF-beta superfamily member, crucially influences early skeletal formation and acts as a bone density negative regulator. It counteracts osteogenic BMPs, hindering osteoprogenitor differentiation. BMP-3 initiates signaling via ACVR2B, activating SMAD2-dependent and SMAD-independent pathways, including TAK1 and JNK. Structurally, it forms homodimers with disulfide bonds, interacting with ACVR2B to regulate functions. BMP-3 Protein, Human is the recombinant human-derived BMP-3 protein, expressed by E. coli , with tag free. The total length of BMP-3 Protein, Human is 110 a.a., with molecular weight of ~12 kDa.Artikelnummer | MEXHY-P79077-10UG |
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Hersteller | MedChemExpress |
Hersteller Artikelnummer | HY-P79077-10UG |
Verpackungseinheit | 10 μg |
Mengeneinheit | STK |
Produktinformation (PDF) |
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MSDS (PDF) |
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