Product Description: Boc-Asp(OBzl)-CMK is an inhibitor for IL-1 converting enzyme (ICE, caspase1). Boc-Asp(OBzl)-CMK prevents death of CHP100 neuroblastoma cell, and IL-1β release elicited by the viral coat protein[1].
Formula: C17H22ClNO5
References: [1]Corasaniti MT, et al., HIV-1 coat protein gp120 stimulates interleukin-1beta secretion from human neuroblastoma cells: evidence for a role in the mechanism of cell death. Br J Pharmacol. 2001 Nov;134(6):1344-50.
CAS Number: 172702-58-8
Molecular Weight: 355.81
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Caspase