Bortezomib, CAS 179324-69-7

Proteasome inhibitor

Product Type: Inhibitor

CAS No.: 179324-69-7

MolecularFormula: C19H25BN4O4

Molecular Weight: 384,2

Source: Synthetic

Purity: >98%

Solubility: Soluble in 50 mg/ml DMSO, 35 mg/ml Ethanol

Appearance: White Powder

PubChem CID: 387447

Scientific Background: Potent and selective proteasome inhibitor (Ki=0.6 nM). Inhibits proliferation of a number of tumor cell lines (IC50=7 nM). Inhibits TNF synthesis and FGF-induced angiogenesis. Reversible. Cell permeable.

References: 1. Adams J., et al. (1999) Cancer Res. 59: 2615. 2. Williams S., et al. (2003) Mol. Cancer Ther. 2: 835.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-328-25MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-328-25MG
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK