Brazilein, CAS 600-76-0

Formulation: A solid

Formal Name: 6a,7-dihydro-3,6a,10-trihydroxy-benz[b]indeno[1,2-d]pyran-9(6H)-one

Purity: ≥95%

Formula Markup: C16H12O5

Formula Weight: 284,3

Shelf life (days): 730

CAS Number: 600-76-0

Notes: Brazilein is a phytochemical that has been found in C. sappan and has diverse biological activities.{69019,69020,69021,69022} It is active against E. coli, P. aeruginosa, and methicillin-susceptible S. aureus (MSSA; MICs = 32, 512, and 512 µg/ml), as well as a panel of 10 clinical isolates of methicillin-resistant S. aureus (MRSA; MIC50s = 16-32 µg/ml).{69019} Brazilein (10 µM) inhibits LPS-induced nitric oxide (NO) production in J774A.1 cells.{69020} It is cytotoxic to HepG2, Hep3B, MDA-MB-231, MCF-7, A549, and Ca9-22 cancer cells (IC50s = 3.15, 3.42, 2.36, 3.96, 9.68, and 8.63 µg/ml, respectively).{69021} Brazilein (1-10 µg/ml) also inhibits the proliferation of isolated mouse spleen lymphocytes induced by concanavalin A (Item No. 14951).{69022}

• Artikelnummer: CAY36736-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36736-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe