BRD4 (BD1+BD2) Recombinant

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Encompassing Amino Acids: 49-460

Applications: Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.

Assay Conditions: Assay was performed according to BRD4 (BD1+BD2) TR-FRET Assay Kit (BPS Bioscience #32612) with BRD4 (BD1+BD2) Recombinant titrated at various concentrations as a competitive antagonist to BRD4 (BD1+BD2) GST-Tag Recombinant (BPS Bioscience #31044).

Description: Human Bromodomain containing 4, also known as BRD4, HUNK1, or MCAP, GenBank Accession No. NM_058243, a.a. 49-460 corresponding to bromodomains 1 and 2, with no tag, MW = 46.9 kDa, expressed in an E. coli cell expression system.

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 7.5, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, and 20% glycerol.

Genbank: NM_058243

Storage Stability: Store at -80°C. Stable for >6 months when stored as directed.

Tags: none

Uniprot: O60885

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Rodriguez, RM, et al., J Mol Med (Berl). 2012 May; 90(5): 587-95.
2. Voigt, P, et al., Genome Biol. 2011 Nov 29;12(11):133.

• Artikelnummer: BPS31047
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 31047
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Wirt: Escherichia Coli