BRDT (BD2), GST-tag Recombinant

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Encompassing Amino Acids: 257-382

Applications: Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.

Assay Conditions: Assay was performed according to BRD4 (BD1+BD2) TR-FRET Assay Kit (BPS Bioscience #32612) with BRD4 (BD1+BD2) Recombinant titrated at various concentrations as a competitive antagonist to BRD4 (BD1+BD2) GST-Tag Recombinant (BPS Bioscience #31044).

Description: Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9, GenBank Accession No. NM_207189, a.a. 257 - 382 corresponding to bromodomain 2 with N-terminal GST-tag, MW = 41.7 kDa, expressed in an E. coli expression system.

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Genbank: NM_207189

Storage Stability: At least 6 months at -80°C.

Tags: N-terminal GST-tag

Uniprot: Q58F21

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Pivot-Pajot C., et al., Mol Cell Biol. 2003 Aug; 23(15): 5354-65.
2. Moriniére J., et al., Nature. 2009 Oct 1; 461(7264):664-8.

• Artikelnummer: BPS31060
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 31060
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Wirt: Escherichia Coli