BRK Kinase Assay Kit

Products from BPS Bioscience require a minimum order value above 400€

Applications: Study enzyme kinetics and screen small molecule inhibitors for drug discovery and high throughput screening (HTS) applications.

Background: Breast Tumor Kinase (BRK, also known as Tyrosine-protein kinase-6 or PKT6) is a non-receptor protein with tyrosine kinase activity. BRK is involved in epithelial differentiation and apoptosis. It interacts with multiple proteins and is involved in several signaling pathways, like activating STAT3 and STAT5B to promote cell proliferation. It is involved in cancer progression, migration and evasion, namely in breast cancer. Targeting BRK kinase activity via small molecule inhibitors may be a viable therapeutic approach for breast cancer.

Contraindications: The final concentration of DMSO in the assay should not exceed 1%.

Description: The breast tumor kinase (BRK) Kinase Assay Kit is designed to measure BRK tyrosine kinase activity for screening and profiling applications using ADP-Glo™ as a detection reagent. 

Storage Stability: This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.

Supplied As: The assay kit comes in a convenient 96-well format, with enough purified recombinant BRK kinase, kinase substrate, ATP, and kinase assay buffer for 100 enzyme reactions.

Uniprot: Q13882

Warnings: Avoid freeze/thaw cycles

Biosafety Level: Not applicable (BSL-1)

• Artikelnummer: BPS78841
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 78841
• Green Labware: Nein
• Verpackungseinheit: 96 reactions
• Mengeneinheit: PAK