Solubility: May be dissolved in DMSO (40 mg/ml) or Ethanol (5 mg/ml)
Appearance: Cream solid
PubChem CID: 2921148
Scientific Background: BRL-50481 is a selective phosphodiesterase 7 (PDE7) inhibitor. In the presence of BRL-50481 the activity of hrPDE7A1 was inhibited against the phosphodiesterase (PDE3) and (PDE4) (1). Studies have suggested a potential role of BRL-50481 in the treatment of osteoporosis (2).
References: 1. Smith J., et al. (2004) Molecular Biology Pharmacology. 66(6): 1679-89. 2. Pekkinen M., et al. (2008) Bone. 43(1): 84-91.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.