Formulation: A solution in ethanol
Formal Name: 1,1′-[[2-[4-[2-[[2-[bis(2-hydroxydodecyl)amino]ethyl](2-hydroxydodecyl)amino]ethyl]-1-piperazinyl]ethyl]imino]bis-2-dodecanol
Purity: ≥95%
Formula Markup: C70H145N5O5
Formula Weight: 1136,9
Shelf life (days): 365
CAS Number: 1220890-25-4
Notes: C12-200 is a branched-chain ionizable cationic lipidoid.{69044,69045} It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA, siRNA, or self-amplifying RNA (saRNA). Administration of human erythropoietin (EPO) mRNA or factor VII siRNA in C12-200-containing LNPs increases serum EPO levels and reduces factor VII serum levels, respectively, in mice.{69044}