C18 Ceramide-d7 (d18:1-d7/18:0), CAS 1840942-14-4

Formulation: A solution in methanol:chloroform (10:90)

Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl-15,15,16,16,17,17,17-d7]-octadecanamide

Purity: ≥99% deuterated forms (d1-d7)

Formula Markup: C36H64D7NO3

Formula Weight: 573

Shelf life (days): 730

CAS Number: 1840942-14-4

Notes: C18 Ceramide-d7 is intended for use as an internal standard for the quantification of C18 ceramide (Item No. 19556) by GC- or LC-MS. C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice.{40029} Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells.{13918} It is selectively down-regulated in 32 human head and neck squamous cell carcinoma tumor tissues as compared to non-squamous tumor tissues. C18 Ceramide concentration is significantly higher in muscle tissue of type 2 diabetic patients compared with non-diabetic patients and is positively correlated to body mass index and inversely related to insulin sensitivity.{40030}

• Artikelnummer: CAY22788-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22788-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung