Formulation: A crystalline solid
Formal Name: N,N’-[[3’,6’-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9’-[9H]xanthene]-2’,7’-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]]-glycine, 1,1’-bis[(acetyloxy)methyl] ester
Purity: ≥90%
Formula Markup: C46H46N2O23
Formula Weight: 994,9
Shelf life (days): 1460
CAS Number: 148504-34-1
Notes: Calcein AM is a cell-permeable dye that, upon entering live cells, is cleaved by intracellular esterases, leaving membrane-impermeant calcein (Item No. 16221), a fluorescent indicator with absorption and emission maxima of 494 and 517 nm, respectively. It can be used as an indicator of cell viability, cell-cell communication, cytotoxicity, or changes in intracellular calcium, fluoride, iron, or mercury.{16310,22804} As calcein is a substrate for multidrug resistance-associated protein 1 (MRP1) and multidrug resistance protein 3 (MDR3, P-glycoprotein 3), calcein AM is used to study these proteins and their regulation.{19233,23971,30807}
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