Caldesmon antibody (hHCD)

Clone Name: hHCD

Application Note: IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 93

Positive Control: Endometrial cancer

Specificity/Sensitivity: This antibody is specific to high molecular weight (120-150 kDa) h-caldesmon. The h-caldesmon variant is predominantly expressed in smooth muscle, whereas l-caldesmon (71-80 kD) is found in non-muscle tissue and cells.

Form: Liquid

Buffer (with preservative): PBS, 0.1% BSA, 0.05% Sodium azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Uniprot ID: Q05682

Antigen Species: Human

Immunogen: BALB/C mice were injected with human uterus smooth muscle extract.

Purification: Purified IgG

Conjugation: Unconjugated

Full Name: caldesmon 1

• Artikelnummer: GTX03317-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX03317-500
• Green Labware: Nein
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1
• Human Gene ID: 800
• Wirt: Mouse