Caldesmon antibody (MSVA-538R) HistoMAX™

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Clone Name: MSVA-538R

Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.

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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 93

Positive Control: Colon: A strong caldesmon staining should be seen of the muscularis mucosa and of a membrane-like layer along the basement membranes of crypts (intestinal subepithelial myofibroblasts).

Negative Control: Colon: Normal epithelial cells must not show caldesmon staining.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Uniprot ID: Q05682

Antigen Species: Human

Immunogen: Recombinant human full-length CALD1 protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: caldesmon 1

• Artikelnummer: GTX04451-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04451-500
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Human Gene ID: 800
• Wirt: Rabbit
• Konjugat: Unconjugated