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Calmodulin antibody (J4D8)
Calmodulin antibody (J4D8)
Artikelnummer
GTX57543-100
Verpackungseinheit
100 μl
Hersteller
GeneTex
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Clone Name: J4D8
Light Chain: Kappa
Application Note: WB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 17
Form: Liquid
Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Uniprot ID: P0DP23/P0DP24/P0DP25/P62158
Antigen Species: Human
Immunogen: The clone J4D8 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Calmodulin protein.
Purification: Protein G Purified
Conjugation: Unconjugated
Full Name: calmodulin 2
Light Chain: Kappa
Application Note: WB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 17
Form: Liquid
Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Uniprot ID: P0DP23/P0DP24/P0DP25/P62158
Antigen Species: Human
Immunogen: The clone J4D8 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Calmodulin protein.
Purification: Protein G Purified
Conjugation: Unconjugated
Full Name: calmodulin 2
| Artikelnummer | GTX57543-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX57543-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 μl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine) |
| Klonalität | Monoclonal |
| Methode | Immunofluorescence, Western Blotting, Flow Cytometry, Immunocytochemistry |
| Isotyp | IgG2a |
| Human Gene ID | 805 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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Gernot Ensinger, M.Sc.
Laurent Haze
