CARD11 blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89813.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Concentration:

Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]

Region Sequence: C-QRKTIWVDEDQL

Full Name: caspase recruitment domain family member 11

• Artikelnummer: GTX89813-PEP-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX89813-PEP-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Dog (Canine), Cow (Bovine)
• Methode: ELISA, Blocking, Affinity Purification
• Human Gene ID: 84433