CASC5 antibody (HL2158)

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Clone Name: HL2158

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 265

Specificity/Sensitivity: We do not recommend use of this product for Mouse,Rat.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11;15)(q23;q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jan 2013]

Uniprot ID: Q8NG31

Antigen Species: Human

Immunogen: Synthtic peptide of human CASC5

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: kinetochore scaffold 1

• Artikelnummer: GTX638136-S-25
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX638136-S-25
• Verpackungseinheit: 25 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 57082
• Wirt: Rabbit
• Konjugat: Unconjugated