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Caveolin 1 antibody (4D6)
Caveolin 1 antibody (4D6)
Artikelnummer
GTX01969-500
Verpackungseinheit
500 μl
Hersteller
GeneTex
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Clone Name: 4D6
Light Chain: Kappa
Application Note: WB: 1:4000. IHC-P: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 20
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
Uniprot ID: Q03135
Antigen Species: Human
Immunogen: Prokaryotic recombinant protein corresponding to the N-terminus domain of the human caveolin-1 molecule.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: caveolin 1
Light Chain: Kappa
Application Note: WB: 1:4000. IHC-P: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 20
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
Uniprot ID: Q03135
Antigen Species: Human
Immunogen: Prokaryotic recombinant protein corresponding to the N-terminus domain of the human caveolin-1 molecule.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: caveolin 1
| Artikelnummer | GTX01969-500 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX01969-500 |
| Green Labware | Nein |
| Verpackungseinheit | 500 μl |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (paraffin), Western Blotting |
| Isotyp | IgG2a |
| Human Gene ID | 857 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
