CBL-B TR-FRET Assay Kit

Products from BPS Bioscience require a minimum order value above 400€

Applications: Great for screening small molecular inhibitors for drug discovery and HTS applications.

Description: Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B) is an E3 ubiquitinprotein ligase that functions as a negative regulator of T-cell activation. It is a promising drug target in cancer immunotherapy. The CBL-B TR-FRET Assay Kit is designed to measure CBL-B auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes biotin-labeled Ubiquitin and a terbium-labeled anti-CBL-B antibody to complete the TR-FRET pairing. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications.

Storage Stability: Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.

Supplied As: The CBL-B TR-FRET Assay Kit is designed to measure CBL-B auto-ubiquitination activity in a homogeneous 384 reaction format.

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Jeon, M.S., et al., Immunity. 2004; 21(2): 167-1772. Chiang, Y.J. et al., Nature. 2000; 403: 216-220

• Artikelnummer: BPS79575
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 79575
• Green Labware: Nein
• Verpackungseinheit: 384 rxns.
• Mengeneinheit: PAK