CCR3 antibody (7F12)

Clone Name: 7F12

Application Note: IHC-Fr: 1:50 - 1:200. FACS: 1:100 - 1:800. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 41

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]

Uniprot ID: P51677

Antigen Species: Human

Immunogen: Human CCR3 transfected 293 cells

Purification: Protein G purified

Conjugation: Unconjugated

Full Name: C-C motif chemokine receptor 3

• Artikelnummer: GTX52514-50
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX52514-50
• Green Labware: Nein
• Verpackungseinheit: 50 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (frozen), Flow Cytometry
• Isotyp: IgG2
• Human Gene ID: 1232
• Wirt: Rat