CD11b antibody (M1/70)

Clone Name: M1/70

Light Chain: Kappa

Product Description: The M1/70 antibody reacts with human and mouse CD11b, also known as integrin αalpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin αreceptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrin αs are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin αreceptors consist of distinct combinations of integrin αchains which are differentially expressed. integrin αalpha M (CD11b) assembles with integrin αbeta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Form: Liquid

Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.

Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species: Mouse

Immunogen: B10 mouse spleen cells enriched for T cells

Purification: Purified by affinity chromatography

Conjugation: Unconjugated

Full Name: integrin alpha M

• Artikelnummer: GTX00608-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX00608-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Primate, Cynomolgus Monkey (Primate), Rhesus Monkey (Primate), Rabbit
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Immunoprecipitation, Neutralization, Immunocytochemistry, Inhibition Assay, Fluorescence-Activated Cell Sorting (FACS)
• Isotyp: IgG2b
• Human Gene ID: 16409
• Wirt: Rat