CD13 antibody (38C12)

Clone Name: 38C12

Application Note: IHC-P: 1:80. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 110

Form: Liquid

Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.

Concentration:

Background: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]

Uniprot ID: P15144

Antigen Species: Human

Immunogen: Recombinant prokaryotic fusion protein corresponding to the C-terminal region of the extracellular domain.

Purification: Unpurified

Conjugation: Unconjugated

Full Name: alanyl aminopeptidase, membrane

• Artikelnummer: GTX01910-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX01910-500
• Green Labware: Nein
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1
• Human Gene ID: 290
• Wirt: Mouse