CD152/CTLA-4 Polyclonal Antibody, Rabbit

Abbreviation: CD152/CTLA-4

Target Synonym: CTLA4;ALPS5;CD;CD152;CELIAC3;CTLA-4;GRD4;GSE;IDDM12

Conjugation: Unconjugated

UNIProt ID: P16410

Background: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CD152/CTLA-4

Dilution: WB 1:500-1:2000,IHC 1:50-1:200

• Artikelnummer: ELSE-AB-93268-200
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-93268-200
• Green Labware: Nein
• Verpackungseinheit: 200 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Western Blotting, Immunohistochemistry
• Isotyp: IgG
• Wirt: Rabbit