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CD19 antibody (HIB19) (PE-Cy5)
CD19 antibody (HIB19) (PE-Cy5)
Artikelnummer
GTX01455-09-100
Verpackungseinheit
100 test
Hersteller
GeneTex
Verfügbarkeit:
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Clone Name: HIB19
Light Chain: Kappa
Product Description: The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.The HIB19 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
Application Note: FACS: 0.25 μg (5 μl) for 10⁵-10⁸ cells in 100 μl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 61
Form: Liquid
Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Concentration: 0.05 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
Uniprot ID: P15391
Purification: Purified by affinity chromatography
Conjugation: PE-Cy5
Full Name: CD19 molecule
Light Chain: Kappa
Product Description: The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.The HIB19 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
Application Note: FACS: 0.25 μg (5 μl) for 10⁵-10⁸ cells in 100 μl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 61
Form: Liquid
Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Concentration: 0.05 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
Uniprot ID: P15391
Purification: Purified by affinity chromatography
Conjugation: PE-Cy5
Full Name: CD19 molecule
| Artikelnummer | GTX01455-09-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX01455-09-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 test |
| Mengeneinheit | PAK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Flow Cytometry |
| Isotyp | IgG1 |
| Human Gene ID | 930 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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