CD20/ MS4A1 (B-Cell Marker)(MS4A1/3411), 0.2mg/mL

Description: Recognizes a protein of 30-33 kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre-B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin's disease, particularly of lymphocyte predominant type. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, with BSA

Concentration: 0.2 mg/mL

Storage buffer: PBS, 0.05% BSA, 0.05% azide

Product Origin: Animal

Clone: MS4A1/3411

Entrez Gene ID: 931

Immunogen: A recombinant fragment (around aa 213-297) of human MS4A1 protein (exact sequence is proprietary)

Verified AB Applications: Flow (verified)/IF (verified)/IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: Flow (verified)/IF (verified)/IHC, FFPE (verified)/WB (verified)

• Artikelnummer: BTMBNUB3411-500
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUB3411-500
• Green Labware: Nein
• Verpackungseinheit: 500 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Flow Cytometry, Immunohistochemistry
• Isotyp: IgG2b kappa
• Wirt: Mouse