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Encompassing Amino Acids: 19-247
Application: Useful for studying protein binding and for screening small molecules and antibodies.
Description: Human CD226 antigen also known as DNAX accessory molecule 1 (DNAM-1), GenBank Accession No. NM_006566, a.a. 19-247 fused to Fc region of human IgG1, expressed in a HEK293 cell expression system. MW = 52.8 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20%glycerol
Genbank: NM_006566
Host Cell Line: HEK293
Storage Stability: At least 6 months at -80°C.
Tags: Fc fusion (Human IgG1)
Uniprot: Q15762
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Bottino, C., et al., J. Exp. Med. 2003; 198(4): 557-567.
2. Hafler, J., et al., Genes Immun. 2009; 10: 5-10.
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