CD27 antibody (MSVA-027M) HistoMAX™

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Clone Name: MSVA-027M

Light Chain: Kappa

Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.

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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 29

Positive Control: Tonsil: A strong, membranous staining should be seen in the majority of interfollicular lymphocytes but also in a fraction of lymphocytes in the germinal centres and the mantle zone.

Negative Control: Tonsil: CD27 staining should be absent in all epithelial cells and a fraction of lymphocytes.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Uniprot ID: P26842

Antigen Species: Human

Immunogen: Recombinant human CD27 protein fragment (aa 28-170)

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: CD27 molecule

• Artikelnummer: GTX04394-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04394-500
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2b
• Human Gene ID: 939
• Wirt: Mouse
• Konjugat: Unconjugated