Target Synonym: CD27;S152;S152. LPFS2;T14;TNFRSF7;Tp55;S152.LPFS2
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Immunogen: Recombinant fusion protein of human CD27
Dilution: WB 1:500-1:2000
Calculated MW: 29kDa
Observed MW: 50kDa
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