CD3 antibody (Hit3a)

Clone Name: Hit3a

Light Chain: Kappa

Product Description: The Hit3a antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.The Hit3a antibody is a widely used phenotypic marker for human T cells. In addition, binding/cross-linking of Hit3a antibody to CD3e can induce cell activation. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3.

Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Form: Liquid

Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.

Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Uniprot ID: P04234/P09693/P20963/P07766

Purification: Purified by affinity chromatography

Conjugation: Unconjugated

Full Name: CD3d molecule/CD3e molecule/CD3g molecule/CD247 molecule

• Artikelnummer: GTX01459-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX01459-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Primate
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (frozen), Neutralization, Immunocytochemistry, Inhibition Assay, Fluorescence-Activated Cell Sorting (FACS)
• Isotyp: IgG2a
• Human Gene ID: 916
• Wirt: Mouse