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CD3 epsilon antibody (MSVA-003R) HistoMAX™
CD3 epsilon antibody (MSVA-003R) HistoMAX™
Artikelnummer
GTX04389-500
Verpackungseinheit
500 μl
Hersteller
GeneTex
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Clone Name: MSVA-003R
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 23
Positive Control: Tonsil: A moderate to strong membranous staining should be seen in all T-cells in the interfollicular T-zones and in the germinal centres (few cells).
Negative Control: Tonsil: All epithelial structures and B-cells should not show any CD3 immunostaining.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Uniprot ID: P07766
Antigen Species: Human
Immunogen: A synthetic peptide from human CD3e protein (around aa 20-40)
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: CD3e molecule
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 23
Positive Control: Tonsil: A moderate to strong membranous staining should be seen in all T-cells in the interfollicular T-zones and in the germinal centres (few cells).
Negative Control: Tonsil: All epithelial structures and B-cells should not show any CD3 immunostaining.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Uniprot ID: P07766
Antigen Species: Human
Immunogen: A synthetic peptide from human CD3e protein (around aa 20-40)
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: CD3e molecule
| Artikelnummer | GTX04389-500 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX04389-500 |
| Green Labware | Nein |
| Verpackungseinheit | 500 μl |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (paraffin) |
| Isotyp | IgG |
| Human Gene ID | 916 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
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