CD35 / CR1(E11), 1mg/mL

CD35 / CR1(E11), 1mg/mL
Artikelnummer
BTMBNUM0040-50
Verpackungseinheit
50 uL
Hersteller
Biotium

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Description: Recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21 /CD35 /CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: E11

Entrez Gene ID: 1378

Immunogen: Intact human monocytes

Expected AB Applications: ELISA (published for clone)/Flow, surface (published for clone)/WB (published for clone)

Verified AB Applications: IHC (FFPE) (verified)

Z-Antibody Applications: Flow, surface (published)/ELISA (published)/IHC, FFPE (verified)/WB (published)
Mehr Informationen
Artikelnummer BTMBNUM0040-50
Hersteller Biotium
Hersteller Artikelnummer BNUM0040-50
Green Labware Nein
Verpackungseinheit 50 uL
Mengeneinheit STK
Reaktivität Human, Primate, Cynomolgus Monkey (Primate), Rhesus Monkey (Primate)
Klonalität Monoclonal
Methode Western Blotting, ELISA, Flow Cytometry, Immunohistochemistry
Isotyp IgG1 kappa
Wirt Mouse
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