CD36 (Platelet & Microvessel Marker)(1A7), 1mg/mL

Description: This antibody recognizes a protein of 80-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: 1A7

Entrez Gene ID: 948

Immunogen: Human CD36 from platelets

Expected AB Applications: Functional studies (published for clone)/IP (published for clone)/WB (published for clone)

Z-Antibody Applications: Functional studies (published)/IP (published)/WB (published)

• Artikelnummer: BTMBNUM0299-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM0299-50
• Green Labware: Nein
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Western Blotting, Functional Studies
• Isotyp: IgG2b kappa
• Wirt: Mouse