CD43(Bra7G), 1mg/mL

Description: This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop V). Epitope of MAb Bra7G is clearly different from that of MAb DF-T1, called b as opposed to a for DF-T1. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: Bra7G

Entrez Gene ID: 6693

Immunogen: Immature pluripotent human leukemia K562 cells

Expected AB Applications: Flow, surface (published for clone)/IP (published for clone)

Verified AB Applications: IF (verified)/IHC (FFPE) (verified)

Z-Antibody Applications: Flow, surface (published)/IF (verified)/IHC, FFPE (verified)/IP (published)

• Artikelnummer: BTMBNUM0302-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM0302-50
• Green Labware: Nein
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Flow Cytometry, Immunohistochemistry
• Isotyp: IgM kappa
• Wirt: Mouse