CD47(B6H12.2), 1mg/mL

Description: This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: B6H12.2

Entrez Gene ID: 961

Immunogen: Intact CD47 purified from placenta

Expected AB Applications: Functional studies (published for clone)/IP (published for clone)/WB (published for clone)

Verified AB Applications: Flow (surface) (verified)/IF (verified)

Z-Antibody Applications: IF (published)/Flow, surface (verified)/Functional studies (published)/IF (verified)/IP (published)/WB (published)

• Artikelnummer: BTMBNUM0437-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM0437-50
• Green Labware: Nein
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Flow Cytometry, Functional Studies
• Isotyp: IgG1 kappa
• Wirt: Mouse