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Encompassing Amino Acids: 19-139
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Description: Human recombinant CD47 protein, also known as MER6, GenBank Accession No. BC_102884, a.a. 19-139 expressed in a HEK293 cell expression system. MW = 14.6 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.
Endotoxin Level: <1 EU/µg
Format: Aqueous buffer solution
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_001777
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal His-tag
Uniprot: Q08722
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Lavender, K.G., et al., Blood. 2013 Dec;122(25):4013-20.2. Zhao, X., et al., Mol Ther. 2013 Oct 21(10):1811.